Preheat your oven to 375°F (190°C). In a large mixing bowl, combine the ground beef, shredded cheddar cheese, chopped bacon, breadcrumbs, milk, ketchup, mustard, Worcestershire sauce, garlic powder, onion powder, salt, black pepper, eggs, and diced onions. Mix everything thoroughly until well incorporated, but be careful not to overmix, as this can make the meatloaf dense and tough.
Line a baking sheet with parchment paper or lightly grease a loaf pan. Transfer the meat mixture onto the baking sheet and shape it into a loaf, or press it into the loaf pan. Ensure the meatloaf is even in thickness for proper cooking. If you’re using a loaf pan, leave a little space on the sides to allow excess fat to drain.
Brush the top of the meatloaf with BBQ sauce for extra flavor and a caramelized crust. This step adds a smoky-sweet glaze that enhances the overall taste. For an added cheeseburger-like effect, you can layer on extra shredded cheddar cheese or place bacon strips on top before baking.
Place the meatloaf in the preheated oven and bake for 50-60 minutes or until the internal temperature reaches 160°F (71°C). If you want a crispier crust, broil the meatloaf for the last 5 minutes of cooking. About 10 minutes before it finishes baking, you can add extra cheese or bacon bits on top for a crispy, cheesy topping.
Once baked, remove the meatloaf from the oven and let it rest for about 10 minutes. This helps retain its juices and makes slicing easier. Serve warm with mashed potatoes, roasted vegetables, or a fresh green salad. Leftovers can be used for sandwiches or crumbled into pasta dishes for added flavor.