Preheat your oven to 375°F and lightly grease a baking dish. This prevents sticking and helps the chicken cook evenly.
In a bowl, mix the softened cream cheese, mozzarella, Parmesan, garlic powder, onion powder, salt, and pepper. Stir until smooth and well combined.
Place the chicken breasts in the baking dish. Spread the cream cheese mixture evenly over each piece. For extra texture, sprinkle breadcrumbs on top.
Bake uncovered for 30 minutes or until the chicken is cooked through and the top is golden brown. The internal temperature should reach 165°F.
Remove from the oven and let the chicken rest for 5 minutes. Garnish with chopped green onions or parsley before serving. For another delicious baked chicken dish, try Baked Crispy Chicken Breast.